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What it is
Tesamorelin is a synthetic analog of growth hormone–releasing hormone (GHRH) engineered to improve stability and receptor selectivity for the GHRH receptor (GHRH-R).
Research context
Used in vitro to interrogate somatotroph signaling via cAMP/PKA and phospholipase pathways, Tesamorelin helps model GH axis regulation at the pituitary level. It’s useful for mapping ligand–receptor dynamics, receptor desensitization, and biased signaling profiles compared with native GHRH and other secretagogues.
Research relevance
  • Dissecting GHRH-R pharmacology and downstream GH/IGF-axis transcriptional programs.
  • Comparing receptor kinetics and stability versus native ligands.
  • Evaluating receptor coupling (Gs vs ancillary pathways) and feedback mechanisms in cell systems.
Common lab uses (examples)
  • Reporter assays (CRE-luc) for GHRH-R activation.
  • Time-course phosphorylation and transcriptomic profiling after stimulation.
  • Structure–activity relationship (SAR) benchmarking against other GHRH analogs.
Compliance
For laboratory research use only. Not for human or animal consumption.
 
 
 
Specs
  • Purity: ≥98% (HPLC)
  • Form: Lyophilized powder (vials)
  • Solubility: Sterile Water / Bacteriostatic Water / DMSO (depending on protocol)
  • Molecular Weight (approx.): ~190 Da
  • Appearance: White to off-white crystalline/lyophilized powder
Lab Notes
  • Storage (dry): −20 °C long-term, protected from light and humidity
  • After reconstitution: 2–8 °C (refrigerated); use within standard lab stability window
  • Handling: Maintain aseptic conditions; aliquot to minimize freeze–thaw cycles
  • Reconstitution: Dissolve in bacteriostatic water or sterile solution under sterile technique
Compliance
🔬 For laboratory research only. Not for human consumption, clinical use, or veterinary use.

Tesamorelin 5mg

SKU: #007
$55.00Price

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