What it is
Nicotinamide adenine dinucleotide (NAD⁺) is a ubiquitous redox cofactor and enzymatic substrate central to energy metabolism, DNA repair, and cell signaling. While not a peptide, it’s commonly included in metabolism-focused research catalogs.
Research context
NAD⁺ participates in redox reactions (NAD⁺/NADH), and serves as a substrate for sirtuins, PARPs, and CD38/CD157 ectoenzymes. Manipulating intracellular NAD⁺ levels in vitro helps reveal how cells balance energy production, repair processes, and signaling under stress.
Research relevance
Probing mitochondrial function, glycolytic/oxidative flux, and redox balance.
Investigating PARP-dependent DNA damage responses and sirtuin-mediated deacetylation events.
Studying extracellular NADase activity and calcium signaling via cyclic ADP-ribose pathways.
Common lab uses (examples)
Seahorse/flux assays coupled with NAD(H) quantitation.
Sirtuin/PARP activity readouts and chromatin acetylation status.
Enzymology with CD38/CD157 and metabolomics of NAD⁺ salvage pathways.
Compliance
For laboratory research use only. Not for human or animal consumption.
 
 
 
Specs
Purity: ≥98% (HPLC)
Form: Lyophilized powder (vials)
Solubility: Sterile Water / Bacteriostatic Water / DMSO (depending on protocol)
Molecular Weight (approx.): ~190 Da
Appearance: White to off-white crystalline/lyophilized powder
Lab Notes
Storage (dry): −20 °C long-term, protected from light and humidity
After reconstitution: 2–8 °C (refrigerated); use within standard lab stability window
Handling: Maintain aseptic conditions; aliquot to minimize freeze–thaw cycles
Reconstitution: Dissolve in bacteriostatic water or sterile solution under sterile technique
Compliance
🔬 For laboratory research only. Not for human consumption, clinical use, or veterinary use.