Overview
IGF-1 LR3 (Long-Arginine3 Insulin-Like Growth Factor-1) is a synthetic analog of IGF-1 that has been developed for research purposes. It is commonly used in laboratory studies investigating cell signaling, protein expression, and growth factor activity. Structural modification at position three and extension of the amino acid sequence provide IGF-1 LR3 with greater experimental stability, making it suitable for evaluating receptor interactions and cellular pathway dynamics in controlled systems.
Research Context
In experimental models, IGF-1 LR3 has been studied for its binding affinity to IGF-1 receptors and its role in activating signaling cascades such as PI3K/Akt and MAPK. Researchers have employed it to investigate mechanisms of cell proliferation, DNA activity, nutrient transport, and metabolic regulation in vitro and in vivo laboratory settings.
Research Relevance
IGF-1 LR3 serves as a reference peptide for examining growth factor signaling and cellular communication. Its extended half-life provides researchers with a framework to evaluate long-term receptor activity, anabolic signaling pathways, and cellular adaptation processes. Because of these attributes, IGF-1 LR3 remains a significant tool in biochemical, molecular, and physiological research.
⚠️ Compliance Disclaimer:
For Laboratory Research Use Only. Not for Human or Animal Consumption.
Specs
Purity: ≥98% (HPLC)
Form: Lyophilized powder (vials)
Solubility: Sterile Water / Bacteriostatic Water / DMSO (depending on protocol)
Molecular Weight (approx.): ~190 Da
Appearance: White to off-white crystalline/lyophilized powder
Lab Notes
Storage (dry): −20 °C long-term, protected from light and humidity
After reconstitution: 2–8 °C (refrigerated); use within standard lab stability window
Handling: Maintain aseptic conditions; aliquot to minimize freeze–thaw cycles
Reconstitution: Dissolve in bacteriostatic water or sterile solution under sterile technique
Compliance
🔬 For laboratory research only. Not for human consumption, clinical use, or veterinary use.
