What it is
“GLP-3” isn’t a widely standardized human peptide name like GLP-1 or GLP-2. In some research contexts, “GLP-3” is used informally to refer to glucagon-like peptide family constructs, multi-agonists, or exploratory analogs examined for receptor pharmacology across GCGR/GLP-1R/GLP-2R families. Because nomenclature varies, researchers typically verify the exact sequence and target profile prior to experiments.
Research context
Work labeled under “GLP-3” often explores incretin family signaling, receptor selectivity, and cross-talk between GLP-1R, GLP-2R, and related class B GPCRs. Studies focus on cAMP production, receptor trafficking, β-arrestin recruitment, and proteolytic stability (e.g., DPP-IV susceptibility/resistance).
Research relevance
Probing class B GPCR pharmacology in the incretin/glucagon family.
Mapping potency/efficacy across GLP-1R vs GLP-2R and assessing biased signaling.
Assessing degradation kinetics and analog stability in serum or enzyme-rich media.
Common lab uses (examples)
cAMP accumulation assays in GLP-receptor–expressing cell lines.
β-arrestin recruitment and receptor internalization imaging.
LC-MS stability tests in the presence of DPP-IV or neutral endopeptidases.
Compliance
For laboratory research use only. Not for human or animal consumption.
 
 
 
Specs
Purity: ≥98% (HPLC)
Form: Lyophilized powder (vials)
Solubility: Sterile Water / Bacteriostatic Water / DMSO (depending on protocol)
Molecular Weight (approx.): ~190 Da
Appearance: White to off-white crystalline/lyophilized powder
Lab Notes
Storage (dry): −20 °C long-term, protected from light and humidity
After reconstitution: 2–8 °C (refrigerated); use within standard lab stability window
Handling: Maintain aseptic conditions; aliquot to minimize freeze–thaw cycles
Reconstitution: Dissolve in bacteriostatic water or sterile solution under sterile technique
Compliance
🔬 For laboratory research only. Not for human consumption, clinical use, or veterinary use.